Vancomycin clearance compared to creatinine clearance by timed urine collection in the intensive care unit
In critically ill patients who warrant medical, pulmonary, or cardiac ICU admission, the ratio of total vancomycin clearance to mCLcr measured by timed urine collection may differ from other populations. CLv and the 2021 CKD-EPI creatinine equation may be more correlated to mCLcr by timed urine collection. Larger studies are needed to confirm these results.
Authors
- Andrew Chantha Hean (ORCID: https://orcid.org/0000-0002-8340-2296)
- Frank Chu (ORCID: https://orcid.org/0000-0001-7758-4444)
- Linda Awdishu (ORCID: https://orcid.org/0000-0002-3187-3264)
- Rinoj Mathew
Institutions
- University of California, San Francisco (US)
- University of California, Irvine (US)
- University of California San Diego (US)
- San Francisco Department of Public Health (US)
- Irvine University (US)
- University of San Francisco (US)
- Western University of Health Sciences (US)
Publication Details
- Journal
- International Journal of Antimicrobial Agents
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1016/j.ijantimicag.2025.107704
- Primary Topic
- Urinary Tract Infections Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00