Cognitive predictors of daily activity performance
These findings suggest that cognitive function, particularly Global and Attention & Processing domains, and AD pathological burden play significant, complementary roles in IADL performance among CN older adults. Findings may be used to inform the development of sensitive functional assessments in preclinical AD that focus on key deficits, and later to develop interventions targeting important modifiable factors and compensatory rehabilitative methods to improve IADL performance in everyday life.
Authors
- Nicole S. McKay (ORCID: https://orcid.org/0000-0003-4123-2548)
- Alyssa Weakley (ORCID: https://orcid.org/0000-0002-2644-9960)
- Audrey A. Keleman (ORCID: https://orcid.org/0000-0003-1025-3100)
- Peter R Millar (ORCID: https://orcid.org/0000-0003-4588-739X)
- Susan Lynn Stark (ORCID: https://orcid.org/0000-0002-2816-7158)
- Rebecca M. Bollinger (ORCID: https://orcid.org/0000-0002-1931-8372)
- Beau M. Ances (ORCID: https://orcid.org/0000-0003-3862-7397)
- Erin R. Foster (ORCID: https://orcid.org/0000-0003-1625-2125)
- Jason J. Hassenstab
- John C. Morris
- Tammie L.S. Benzinger
Institutions
- Washington University in St. Louis (US)
- University of California, Davis (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_107600
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00