Baseline Fatigue and Severe Toxic Effects in Patients With Cancer Receiving Systemic Therapy
This cohort study found that baseline patient-reported fatigue was associated with an increased risk of cancer treatment-related toxic effects. Fatigue assessments at treatment initiation may serve as an early clinical marker of risk for toxic effects and may help inform personalized treatment strategies and symptom monitoring.
Authors
- Michael Fisch (ORCID: https://orcid.org/0000-0001-5312-403X)
- Joseph M. Unger (ORCID: https://orcid.org/0000-0002-5191-0317)
- Dawn L. Hershman
- Salene M. W. Jones
- N. Lynn Henry
Institutions
- University of Michigan (US)
- Society of Critical Care Medicine (US)
- Fred Hutch Cancer Center (US)
- Columbia University (US)
Publication Details
- Journal
- JAMA Oncology
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1001/jamaoncol.2025.5549
- Primary Topic
- Cancer survivorship and care
- Type
- article
- Field-Weighted Citation Impact
- 0.00