Blood biomarkers and/or neuropsychological assessment? Optimization of the screening protocols for the early stages of Alzheimer's disease
Our study suggests that the combination of neuropsychological tests and blood biomarkers could improve diagnostic performance in the early stages of AD. However, the fact that the biomarker's importance in the statistical models was greater partially challenges the utility of cognitive assessments, particularly for screening purposes and in situations where clinical time may be limited.
Authors
- María Díez‐Cirarda (ORCID: https://orcid.org/0000-0001-6768-189X)
- Cristina Delgado‐Alonso (ORCID: https://orcid.org/0000-0002-8821-1317)
- Ulises Gómez‐Pinedo
- Juan Ignacio López‐Carbonero (ORCID: https://orcid.org/0000-0002-2825-1851)
- Jordi A. Matías‐Guiu (ORCID: https://orcid.org/0000-0001-5520-2708)
- Jorge Matías‐Guiu (ORCID: https://orcid.org/0000-0001-8162-9043)
- María Valles‐Salgado
- María Cruz Cárdenas‐Fernández
- Esther Valiente‐Gordillo
- María José Gil‐Moreno
- Isabel Ortega‐Madueño
Institutions
- Hospital Clínico San Carlos (ES)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_102569
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00