PD-1 inhibitor improves radiosensitivity by tumor vessel normalization
PD-1 inhibitors improve radiosensitivity through vasculature and immune reprogramming, and vessel normalization may be a biomarker for distinguishing patients who will benefit from radiotherapy after induction immunotherapy.
Authors
- Xiangyan Zhang (ORCID: https://orcid.org/0009-0005-7905-6983)
- Jiaying Deng
- Xiangli Ma
- Quanxin Wang
- Qi Liu
- Kuaile Zhao
- Jingyi Shen
- Shengnan Hao
- Ihsuan Tseng
- Yun Chen
- Hongcheng Zhu
- Zhaolu Kong
- Dashan Ai
Institutions
- Shanghai Medical College of Fudan University (CN)
- Fudan University (CN)
- Fudan University Shanghai Cancer Center (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- Shanghai Institute of Hematology (CN)
Publication Details
- Journal
- British Journal of Cancer
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1038/s41416-025-03315-8
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00