Hepatitis B Vaccination Histories in Persons with HIV Needing Revaccination

Regardless of past vaccine records, antibody titers should be checked in PWH for revaccination needs. The recently approved long-acting (LA) and injectable antiretroviral treatment (ART) lacks protective effect against HBV, unlike tenofovir-based ART. As the LA ART becomes more widely used, we recommend reassessing serologies and offering the recommended CpG-adjuvanted vaccine series with promising response durability to individuals without seroprotection.

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Publication Details

Journal
JAIDS Journal of Acquired Immune Deficiency Syndromes
Published
2025-12-26
DOI
https://doi.org/10.1097/qai.0000000000003828
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Hepatitis B Vaccination Histories in Persons with HIV Needing Revaccination

Ngan Ta Thi Dieu, Stephanie Caruso, Anchalee Avihingsanon, Karen J. Vigil et al.
JAIDS Journal of Acquired Immune Deficiency Syndromes
Hepatitis B Virus Studies
article

Hepatitis B Vaccination Histories in Persons with HIV Needing Revaccination

Ngan Ta Thi Dieu, Stephanie Caruso, Anchalee Avihingsanon, Karen J. Vigil, Unoda Chakalisa, Triin Umbleja, Sandra Wagner Cardoso, Kristen Marks, Josphat Kosgei, Minhee Kang, Kenneth E. Sherman
article en

Abstract

Regardless of past vaccine records, antibody titers should be checked in PWH for revaccination needs. The recently approved long-acting (LA) and injectable antiretroviral treatment (ART) lacks protective effect against HBV, unlike tenofovir-based ART. As the LA ART becomes more widely used, we recommend reassessing serologies and offering the recommended CpG-adjuvanted vaccine series with promising response durability to individuals without seroprotection.

JAIDS Journal of Acquired Immune Deficiency Syndromes
Hanoi Medical University (VN), Cornell University (US), Kenya Medical Research Institute (KE), Massachusetts General Hospital (US), Cancer Research And Biostatistics (US), HIV Netherlands Australia Thailand Research Collaboration (TH), Frontier Science & Technology Research Foundation, Inc. (US), Botswana Harvard AIDS Institute Partnership (BW), The University of Texas Health Science Center (US), Weill Cornell Medicine (US), Fundação Oswaldo Cruz (BR)
Good health and well-being
Openalex Percentile: Top 30%
Hepatitis B Virus Studies
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