Intermittent Theta Burst Transcranial Magnetic Stimulation Improves Language and Functional Connectivity in Primary Progressive Aphasia
We demonstrate preliminary evidence that personalized functional-network guided iTBS can improve language impairments in a heterogeneous PPA and PPAOS cohort. Furthermore, improvements in language tests were accompanied by increases in functional network connectivity, pointing to a putative neural mechanism of TMS-induced benefits in PPA and PPAOS.
Authors
- Alexandra Touroutoglou (ORCID: https://orcid.org/0000-0001-9679-2433)
- Thiago Paranhos (ORCID: https://orcid.org/0000-0001-6489-1955)
- Nick Watson
- Neguine Rezaii (ORCID: https://orcid.org/0000-0002-8967-9237)
- Daisy Hochberg
- Megan Quimby (ORCID: https://orcid.org/0000-0003-1230-7942)
- Yuta Katsumi (ORCID: https://orcid.org/0000-0003-0413-747X)
- Mark C. Eldaief
- Anna Du
- Brad C. Dickerson
- Bonnie Wong
Institutions
- Harvard University (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70858_106722
- Primary Topic
- Neurobiology of Language and Bilingualism
- Type
- article
- Field-Weighted Citation Impact
- 0.00