Persistent bladder dysfunction after Martius flap repair for a radiation-induced vesicovaginal fistula: A case report

Radiation-induced vesicovaginal fistulae represent one of the most challenging complications of pelvic surgery because irradiated tissues exhibit severe fibrosis, ischemia, and impaired healing. Among various surgical techniques, Martius flap repair is widely employed because it provides a well-vascularized tissue buttress and enhances closure rates. However, while most reports have focused on anatomical success, little attention has been paid to the long-term bladder function after closure. We describe the case of a 50-year-old woman who developed a radiation-induced vesicovaginal fistula after chemoradiotherapy for cervical cancer. The fistula was successfully closed using a Martius flap, and no further vaginal leakage was observed. Nevertheless, during follow-up, she developed persistent bladder dysfunction, characterized by reduced compliance, detrusor overactivity, and nocturnal urinary leakage, which was confirmed by serial urodynamic evaluations. This case illustrates a discrepancy between anatomical closure and functional outcomes. Even after technically successful repairs, latent bladder dysfunction may persist and place patients at risk of upper urinary tract deterioration. Our report emphasizes the importance of incorporating systematic urodynamic follow-up into postoperative care, particularly for complex or irradiated fistulas, to ensure anatomical and functional success. • Successful anatomical closure of a radiation-induced vesicovaginal fistula does not always restore normal bladder function. • Postoperative urodynamic evaluations are imperative to detect latent dysfunction. • This is particularly important for younger women to preserve their long-term urinary tract health.

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Publication Details

Journal
Continence Reports
Published
2025-12-26
DOI
https://doi.org/10.1016/j.contre.2025.100104
Primary Topic
Ureteral procedures and complications
Type
article
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article

Persistent bladder dysfunction after Martius flap repair for a radiation-induced vesicovaginal fistula: A case report

Yoshitaka Kurano, Mio Togo, Takashi Karashima, Kaya Atagi et al.
Continence Reports
Ureteral procedures and complications
article

Persistent bladder dysfunction after Martius flap repair for a radiation-induced vesicovaginal fistula: A case report

Yoshitaka Kurano, Mio Togo, Takashi Karashima, Kaya Atagi, Motoaki Saito, Tomoya Nao, Keiji Inoue, Nobutaka Shimizu, Rie Yoshimura, Satoshi Fukata, Hideo Fukuhara
article en

Abstract

Radiation-induced vesicovaginal fistulae represent one of the most challenging complications of pelvic surgery because irradiated tissues exhibit severe fibrosis, ischemia, and impaired healing. Among various surgical techniques, Martius flap repair is widely employed because it provides a well-vascularized tissue buttress and enhances closure rates. However, while most reports have focused on anatomical success, little attention has been paid to the long-term bladder function after closure. We describe the case of a 50-year-old woman who developed a radiation-induced vesicovaginal fistula after chemoradiotherapy for cervical cancer. The fistula was successfully closed using a Martius flap, and no further vaginal leakage was observed. Nevertheless, during follow-up, she developed persistent bladder dysfunction, characterized by reduced compliance, detrusor overactivity, and nocturnal urinary leakage, which was confirmed by serial urodynamic evaluations. This case illustrates a discrepancy between anatomical closure and functional outcomes. Even after technically successful repairs, latent bladder dysfunction may persist and place patients at risk of upper urinary tract deterioration. Our report emphasizes the importance of incorporating systematic urodynamic follow-up into postoperative care, particularly for complex or irradiated fistulas, to ensure anatomical and functional success. • Successful anatomical closure of a radiation-induced vesicovaginal fistula does not always restore normal bladder function. • Postoperative urodynamic evaluations are imperative to detect latent dysfunction. • This is particularly important for younger women to preserve their long-term urinary tract health.

Continence ReportsVol. 17
Kōchi University (JP)
Good health and well-being
Openalex Percentile: Top 26%
Ureteral procedures and complications
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