Fecal matter transplantation and cognition: a systematic review in Alzheimer’s disease and related disorders

Preliminary evidence suggests FMT may have cognitive benefits in AD patients and recurrent CDI. However, the limited number of studies and the presence of CDI as a common comorbidity highlight the need for larger, controlled trials to better define its role in AD management.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70859_107684
Primary Topic
Clostridium difficile and Clostridium perfringens research
Type
article
Field-Weighted Citation Impact
0.00
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article

Fecal matter transplantation and cognition: a systematic review in Alzheimer’s disease and related disorders

Isabela Alicia Fink, GABRIELLE GUINDANI MAIA, Gabriela Bezerra Sorato, Maria Fernanda Peruci Felippe et al.
Alzheimer s & Dementia
Clostridium difficile and Clostridium perfringens research
article

Fecal matter transplantation and cognition: a systematic review in Alzheimer’s disease and related disorders

Isabela Alicia Fink, GABRIELLE GUINDANI MAIA, Gabriela Bezerra Sorato, Maria Fernanda Peruci Felippe, Jessica Vargas Lopes, Laura Carolina Nardi Motta, Leonardo Bedatti Koehler, Ana Carolina Gomes Petry, Daniel Pasini Gonçalves, Matias Pinheiro de Macêdo Neto
article en

Abstract

Preliminary evidence suggests FMT may have cognitive benefits in AD patients and recurrent CDI. However, the limited number of studies and the presence of CDI as a common comorbidity highlight the need for larger, controlled trials to better define its role in AD management.

Alzheimer s & DementiaVol. 21(S5)
Universidade Federal do Rio Grande do Sul (BR), Universidade Federal de Ciências da Saúde de Porto Alegre (BR), Universidade Luterana do Brasil (BR)
Quality Education
Openalex Percentile: Top 31%
Clostridium difficile and Clostridium perfringens research
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