Study on the Imaging Characteristics of β‐Amyloid (Aβ) Deposition (A) and Neurodegeneration (N) in Subjective Cognitive Decline

SCD patients exhibited specific Aβ deposition patterns, predominantly in the left hemisphere, with mild neurodegeneration. Aβ deposition correlated with executive function, while hippocampal/parahippocampal volume correlated with overall cognitive and language functions. These findings suggest potential imaging biomarkers for early AD diagnosis.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_104213
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Study on the Imaging Characteristics of β‐Amyloid (Aβ) Deposition (A) and Neurodegeneration (N) in Subjective Cognitive Decline

Shuhua Ren, Qi Huang, Fang Xie, Yihui Guan
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Study on the Imaging Characteristics of β‐Amyloid (Aβ) Deposition (A) and Neurodegeneration (N) in Subjective Cognitive Decline

Shuhua Ren, Qi Huang, Fang Xie, Yihui Guan
article en

Abstract

SCD patients exhibited specific Aβ deposition patterns, predominantly in the left hemisphere, with mild neurodegeneration. Aβ deposition correlated with executive function, while hippocampal/parahippocampal volume correlated with overall cognitive and language functions. These findings suggest potential imaging biomarkers for early AD diagnosis.

Alzheimer s & DementiaVol. 21(S2)
Fudan University (CN), Huashan Hospital (CN)
Openalex Percentile: Top 32%
Dementia and Cognitive Impairment Research
DOIOpen Access PDFOpenAlex
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