Ventral intraspinal microstimulation alters neural population-level nociceptive activity in rats including after spinal cord injury

Doubling of the number of electrodes with altered pinch responsiveness after ISMS suggests that ISMS causes a lasting increase in the spatial spread of evoked sensory activity. That this change favored inhibition in 1 cohort is consistent with the possibility of ventral ISMS promoting broad inhibitory control of nociceptive activity.

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Publication Details

Journal
PAIN Reports
Published
2025-12-23
DOI
https://doi.org/10.1097/pr9.0000000000001379
Primary Topic
Pain Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
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article

Ventral intraspinal microstimulation alters neural population-level nociceptive activity in rats including after spinal cord injury

Maria F. Bandres, Jacob G. McPherson
PAIN Reports
Pain Mechanisms and Treatments
article

Ventral intraspinal microstimulation alters neural population-level nociceptive activity in rats including after spinal cord injury

Maria F. Bandres, Jacob G. McPherson
article en

Abstract

Doubling of the number of electrodes with altered pinch responsiveness after ISMS suggests that ISMS causes a lasting increase in the spatial spread of evoked sensory activity. That this change favored inhibition in 1 cohort is consistent with the possibility of ventral ISMS promoting broad inhibitory control of nociceptive activity.

PAIN ReportsVol. 11(1)
Washington University in St. Louis (US)
Openalex Percentile: Top 33%
Pain Mechanisms and Treatments
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