<i>APOE ε4</i> ‐related proteomic profiles in plasma and CSF
Our findings reveal distinct proteomic profiles associated with APOE4 in plasma and CSF. Complex molecular mechanisms are linked to APOE4, both with and without the development of AD pathology. Proteins implicated in APOE4-related pathways may be explored as potential biomarkers for early detection and therapeutic targets.
Authors
- Rik Ossenkoppele (ORCID: https://orcid.org/0000-0003-1584-7477)
- Erik Stomrud (ORCID: https://orcid.org/0000-0002-0841-5580)
- Oskar H. Hansson
- Alexa Pichet Binette
- Lina Lu
- Sebastian Palmqvist
- Shorena Janelidze
- Jacob W. Vogel
- Niklas Mattsson‐Carlgren
Institutions
- Lund University (SE)
- Science for Life Laboratory (SE)
- Skåne University Hospital (SE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_103395
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00