Cerebral White Matter Hyperintensities in a biracial US cohort: prevalence and risk factors
Among our study sample, after adjusting for demographic, clinical, and genetic factors, Black participants had a significantly more likely to have larger WMH lesion volume compared with White participants. This may explain some of the racial differences in rates of Alzheimer's disease and vascular cognitive impairment. Studies are needed to better understand the mechanisms leading to the development of WMH.
Authors
- Russell P. Sawyer (ORCID: https://orcid.org/0000-0003-2426-1929)
- Rhonna Shatz (ORCID: https://orcid.org/0000-0003-3954-8148)
- Oluchi Ekenze (ORCID: https://orcid.org/0000-0002-2510-8427)
- Virginia J. Howard (ORCID: https://orcid.org/0000-0003-4912-9975)
- George Howard (ORCID: https://orcid.org/0000-0002-3068-5720)
- Ya Yuan (ORCID: https://orcid.org/0000-0002-2384-5888)
- Joseph Broderick
- Mary Cushman
- Hyacinth I Hyacinth
- Suzanne E Judd
Institutions
- University of Vermont (US)
- University of Alabama at Birmingham (US)
- University of Cincinnati (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_102224
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00