Temporal analysis and factors associated with visceral leishmaniasis-HIV-AIDS coinfection in an endemic region of Brazil
Specific clinical signs and symptoms differ in frequency between coinfected and non-coinfected individuals, which may help identify clinical patterns and improve differential diagnosis strategies. Although temporal trends indicate a stationary pattern over the past 11 years, strengthened interventions are still needed to reduce the incidence of VL-HIV/AIDS coinfection and mitigate its impact in endemic regions. Our findings highlight the importance of early clinical recognition of coinfection patterns and the implementation of targeted public health strategies to mitigate the impact of VL-HIV in endemic regions.
Authors
- Kely Cristina Garcia Vilena (ORCID: https://orcid.org/0000-0003-2276-6165)
- Felipe Machado Mota (ORCID: https://orcid.org/0000-0001-6094-3404)
- Everton Falcão de Oliveira (ORCID: https://orcid.org/0000-0002-0074-5278)
- Ivair Moura de Souza (ORCID: https://orcid.org/0000-0001-6554-7144)
- Tailma Silva Lino de Souza (ORCID: https://orcid.org/0009-0008-1489-7767)
- Rosilene Rocha Palasson (ORCID: https://orcid.org/0000-0003-1474-7503)
- Elen Ferraz Teston
- Gabrielly Segatto Brito
Institutions
- Universidade Federal de Mato Grosso do Sul (BR)
- Universidade Católica Dom Bosco (BR)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1371/journal.pntd.0013845
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Universidade Federal de Mato Grosso do Sul