227eP Delayed immune-related adverse events in renal cell carcinoma long-term responders to immune checkpoint inhibitors: Incidence, characteristics, and management

Renal cell carcinoma (RCC) is distinct in immuno-oncology due to frequent immune checkpoint inhibitor (ICI) plus tyrosine kinase inhibitor (TKI) combinations, the potential for overlapping toxicities, and prolonged exposure from improved overall survival. We aimed to characterise the toxicity profile in this population, with a particular focus on delayed-onset irAEs.

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Publication Details

Journal
Immuno-Oncology Technology
Published
2025-12-01
DOI
https://doi.org/10.1016/j.iotech.2025.101310
Primary Topic
Renal cell carcinoma treatment
Type
article
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article

227eP Delayed immune-related adverse events in renal cell carcinoma long-term responders to immune checkpoint inhibitors: Incidence, characteristics, and management

M. Smith, M.D. Robinson, N. Cook, D. Romero-Romero et al.
Immuno-Oncology Technology
Renal cell carcinoma treatment
article

227eP Delayed immune-related adverse events in renal cell carcinoma long-term responders to immune checkpoint inhibitors: Incidence, characteristics, and management

M. Smith, M.D. Robinson, N. Cook, D. Romero-Romero, A. Oreilly
article en

Abstract

Renal cell carcinoma (RCC) is distinct in immuno-oncology due to frequent immune checkpoint inhibitor (ICI) plus tyrosine kinase inhibitor (TKI) combinations, the potential for overlapping toxicities, and prolonged exposure from improved overall survival. We aimed to characterise the toxicity profile in this population, with a particular focus on delayed-onset irAEs.

Immuno-Oncology TechnologyVol. 28
Barts Health NHS Trust (GB), Hospital Universitario 12 De Octubre (ES), The Christie NHS Foundation Trust (GB)
Good health and well-being
Openalex Percentile: Top 28%
Renal cell carcinoma treatment
DOIOpen Access PDFOpenAlex
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227eP Delayed immune-related adverse events in renal cell carcinoma long-term responders to immune checkpoint inhibitors: Incidence, characteristics, and management — M. Smith, M.D. Robinson, et al. · Immuno-Oncology Technology (2025) | TGRS Research Map | TGRS