Utilizing the Brain Vasculature to Improve Delivery and Safety of the Next Generation of AD Therapeutics

Taken together, ATVcisLALA has the potential to significantly improve both safety and efficacy of Aβ immunotherapy through enhanced biodistribution mediated by transport across the blood-brain barrier.

Authors

Joy Yu Zuchero

Institutions

Denali Therapeutics (United States) (US)

Publication Details

Journal: Alzheimer s & Dementia
Published: 2025-12-01
DOI: https://doi.org/10.1002/alz70859_102246
Primary Topic: Alzheimer's disease research and treatments
Type: article
Field-Weighted Citation Impact: 0.00

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article

Utilizing the Brain Vasculature to Improve Delivery and Safety of the Next Generation of AD Therapeutics

Joy Yu Zuchero

Dec 1, 2025

Alzheimer s & Dementia

Alzheimer's disease research and treatments

article

Utilizing the Brain Vasculature to Improve Delivery and Safety of the Next Generation of AD Therapeutics

Joy Yu Zuchero

December 1, 2025article en

Abstract

Alzheimer s & DementiaVol. 21(S5)

Denali Therapeutics (United States) (US)

Good health and well-being

Openalex Percentile: Top 33%

Alzheimer's disease research and treatments

DOI Open Access PDF OpenAlex

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Utilizing the Brain Vasculature to Improve Delivery and Safety of the Next Generation of AD Therapeutics — Joy Yu Zuchero · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS