Evaluating the health economic impact of cefepime/enmetazobactam in complicated urinary tract infections in the German setting: a cost analysis from payer perspective

The analysis shows that a higher probability of relapse after antibiotic therapy might be associated with an increase in treatment costs within the German healthcare system. Although per-patient cost differences between cefepime/enmetazobactam and piperacillin/tazobactam are moderate, their cumulative impact at the population level could be substantial, emphasizing the broader health-economic relevance of treatment choice for cUTI.

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Publication Details

Journal
Infection
Published
2025-12-26
DOI
https://doi.org/10.1007/s15010-025-02711-9
Primary Topic
Urinary Tract Infections Management
Type
article
Field-Weighted Citation Impact
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article

Evaluating the health economic impact of cefepime/enmetazobactam in complicated urinary tract infections in the German setting: a cost analysis from payer perspective

Florian Kron, J. D. Roder, Jörg Janne Vehreschild, Sebastian Wingen‐Heimann et al.
Infection
Urinary Tract Infections Management
article

Evaluating the health economic impact of cefepime/enmetazobactam in complicated urinary tract infections in the German setting: a cost analysis from payer perspective

Florian Kron, J. D. Roder, Jörg Janne Vehreschild, Sebastian Wingen‐Heimann, Danila Seidel, Oliver Witzke, Melina S. Kurte, Ann-Cathrine Froitzheim, Oliver A. Cornely
article en

Abstract

The analysis shows that a higher probability of relapse after antibiotic therapy might be associated with an increase in treatment costs within the German healthcare system. Although per-patient cost differences between cefepime/enmetazobactam and piperacillin/tazobactam are moderate, their cumulative impact at the population level could be substantial, emphasizing the broader health-economic relevance of treatment choice for cUTI.

InfectionVol. 54(2)
Goethe University Frankfurt (DE), University of Cologne (DE), FOM University of Applied Sciences for Economics and Management (DE), Düsseldorf University Hospital (DE), Integrated Oncology (United States) (US), Fraunhofer Institute for Translational Medicine and Pharmacology (DE), German Center for Infection Research (DE), QUIRIS Healthcare (DE), University Hospital Frankfurt (DE), Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (DE), University Hospital Cologne (DE), Heinrich Heine University Düsseldorf (DE), University of Duisburg-Essen (DE)
Partnerships for the goals
Openalex Percentile: Top 30%
Urinary Tract Infections Management
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Evaluating the health economic impact of cefepime/enmetazobactam in complicated urinary tract infections in the German setting: a cost analysis from payer perspective — Florian Kron, J. D. Roder, et al. · Infection (2025) | TGRS Research Map | TGRS