The Latin American Spanish Preclinical Alzheimer's Cognitive Composite (LAS‐PACC5): Adapted for Spanish‐Speaking Latino Populations

The LAS-PACC5 showed convergent validity with memory and language measures and successfully distinguished between Latino individuals with and without cognitive impairment, supporting its reliability for assessing overall cognition and detecting cognitive impairment in Spanish-speaking older Latinos. Future research should include longitudinal follow-up, larger samples, and explore associations with AD-related biomarkers, including imaging and blood-based measures.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_105553
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

The Latin American Spanish Preclinical Alzheimer's Cognitive Composite (LAS‐PACC5): Adapted for Spanish‐Speaking Latino Populations

Jairo Enrique Martinez, Rosalinda Medrano, Marta Gonzalez Catalan, Jorge Alcina et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

The Latin American Spanish Preclinical Alzheimer's Cognitive Composite (LAS‐PACC5): Adapted for Spanish‐Speaking Latino Populations

Jairo Enrique Martinez, Rosalinda Medrano, Marta Gonzalez Catalan, Jorge Alcina, Daniel G Saldana, Yakeel T. Quiroz, Isabel Solis, Nikole A Bonillas Félix, Liliana Ramírez Gómez, Clara Vila‐Castelar, Alexandre Closs Fanfa Ribas, Nadeshka J Ramirez‐Perez, Lusiana Martinez, Averi Giudicessi
article en

Abstract

The LAS-PACC5 showed convergent validity with memory and language measures and successfully distinguished between Latino individuals with and without cognitive impairment, supporting its reliability for assessing overall cognition and detecting cognitive impairment in Spanish-speaking older Latinos. Future research should include longitudinal follow-up, larger samples, and explore associations with AD-related biomarkers, including imaging and blood-based measures.

Alzheimer s & DementiaVol. 21(S3)
Harvard University (US), Massachusetts General Hospital (US), Cambridge Systematics (United States) (US)
Quality Education
Openalex Percentile: Top 32%
Dementia and Cognitive Impairment Research
DOIOpen Access PDFOpenAlex
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The Latin American Spanish Preclinical Alzheimer's Cognitive Composite (LAS‐PACC5): Adapted for Spanish‐Speaking Latino Populations — Jairo Enrique Martinez, Rosalinda Medrano, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS