Cerebrospinal fluid fatty acids are better predictors of mild cognitive impairment than Aβ <sub>42</sub> /tau ratio
Our study suggests that changes in fatty acid metabolism precede abnormalities in amyloid and tau in MCI. Thus, strategies that regulate fatty acid metabolism may stem off early cognitive decline in an older population.
Authors
- Alfred K. Njamnshi (ORCID: https://orcid.org/0000-0003-0052-1511)
- Yannick N. Wadop (ORCID: https://orcid.org/0000-0002-8955-1874)
- Xueqiu Jian (ORCID: https://orcid.org/0000-0002-0313-6494)
- Bernard Fongang (ORCID: https://orcid.org/0000-0002-8161-1553)
- Jacob Apibilla Ayembilla (ORCID: https://orcid.org/0000-0002-2164-5962)
- Biniyam Ayele
- Jayandra J. Himali
- Alice Nono Djotsa
- Alfred N. Fonteh
- Sudha Seshadri
- Muralidharan Sargurupremraj
Institutions
- University of Southern California (US)
- Huntington Medical Research Institutes (US)
- University of Miami (US)
- Université de Bordeaux (FR)
- The University of Texas at San Antonio Health Science Center (US)
- Baylor College of Medicine (US)
- Accra Technical University (GH)
- Institute for Neurodegenerative Disorders (US)
- Dr. John T. Macdonald Foundation (US)
- Catholic University of Central Africa (CM)
- Global Brain Health Institute (US)
- Addis Ababa University (ET)
- The University of Texas at San Antonio (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_102952
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00