Transcriptomic signatures in different tissues of anti‐MDA5 positive dermatomyositis: Uncovering genes with predictive potential for RP‐ILD
The activation of the IFN, virus-associated, and aberrant immune response pathways, as well as fatty acid metabolic processes may be involved in MDA5+ DM pathogenesis. IFI27, DEFA3, and RNASE2 may contribute to RP-ILD pathogenesis and serve as biomarkers of MDA5+ DM.
Authors
- S. Wang
- H. Li
- Qian Zhao
- Fei Xue (ORCID: https://orcid.org/0000-0001-7047-8497)
- Hao Wang (ORCID: https://orcid.org/0000-0001-6881-9977)
- Jie Zheng (ORCID: https://orcid.org/0000-0001-9755-5595)
- Cheng Quan (ORCID: https://orcid.org/0000-0002-0127-2716)
- Yutong Su
- Xintian Xu
- Licheng Diao
- Xuemei Zhu
- Yeping Ruan
- Jian Li
- Hua Cao
- Ke Xue
- Yanting Shih
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- Institut Pasteur of Shanghai (CN)
- Center for Excellence in Molecular Cell Science (CN)
- Third People's Hospital of Hangzhou (CN)
- Wuxi No.2 People's Hospital (CN)
- Shanghai Skin Disease Hospital (CN)
- Wuxi People's Hospital (CN)
Publication Details
- Journal
- JDDG Journal der Deutschen Dermatologischen Gesellschaft
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1111/ddg.15937
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.00