SGLT2i, Canagliflozin mitigates amyloid‐beta pathology and cognitive decline in 5XFAD mice
Our study highlights a novel role for SGLT2i in alleviating AD-related pathologies. Moreover, for the first time, our findings emphasize SGLT2i as promising candidates for repurposing in the treatment of neurodegenerative diseases.
Authors
- Marianna Sadagurski (ORCID: https://orcid.org/0000-0002-8203-4612)
- Dulmalika N.H. Manchanayake
- Hashan S. M. Jayarathne
Institutions
- Wayne State University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_104072
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00