The glymphatic system's role in linking cardiometabolic health to cerebral small vessel disease and frailty in Chilean healthy older adults
This research underscores the complex links between cardiometabolic health, glymphatic dysfunction (with PVS as a marker), and frailty, highlighting the differential contributions of cSVD markers to physical frailty in older adults.
Authors
- Daniel Franco O'Byrne
- G. Farías
- Cecilia González Campo
- Carolina Delgado (ORCID: https://orcid.org/0009-0008-2139-1481)
- Ana Maria Castro Laguardia
- Agustin Ibanez
- Paul H Delano
- Vicente Medel
Institutions
- Universidad de Santiago de Chile (CL)
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- Trinity College Dublin (IE)
- Adolfo Ibáñez University (CL)
- University of San Andrés (AR)
- Instituto de Neurología Cognitiva (AR)
- Hospital Clínico de la Universidad de Chile (CL)
- Global Brain Health Institute (US)
- University of Chile (CL)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_106737
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00