Current evidence on umbilical cord and bone marrow stem cell therapy in TBI: A scoping review for future clinical practice
UC-SC and BM-SC therapies both show promise in TBI treatment, with distinct advantages based on injury phase and therapeutic goals. BM-SCs may be more effective in acute TBI due to anti-inflammatory properties, while UC-SCs appear more suitable for chronic TBI, supporting neuroregeneration. Further direct comparative studies and standardized protocols are needed to refine stem cell therapy for TBI.
Authors
- Nasim Amar (ORCID: https://orcid.org/0000-0002-3268-5134)
- Farhad Bal’afif (ORCID: https://orcid.org/0000-0001-8801-3719)
- Donny Wisnu Wardhana (ORCID: https://orcid.org/0000-0003-3958-6072)
- Farhad Bal'afif (ORCID: https://orcid.org/0000-0001-8968-9067)
- Muhammad Azri Ismail
- N. Mohabbath Z. S. Maruapey
- Tommy Alfandy Nazwar
Institutions
- University of Brawijaya (ID)
Publication Details
- Journal
- Surgical Neurology International
- Published
- 2025-12-26
- DOI
- https://doi.org/10.25259/sni_743_2025
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00