Age influence on repetition suppression revealed in the hippocampus with MEG

Neural tuning of the hippocampus during memory formation, namely repetition suppression, changes with age; expressed as greater neural activation in healthy older adults. Characterizing the aging effects on repetition suppression may offer a promising avenue for examination of hippocampal hyperexcitability as a potential biomarker for AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_102845
Primary Topic
Neurobiology of Language and Bilingualism
Type
article
Field-Weighted Citation Impact
0.00
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article

Age influence on repetition suppression revealed in the hippocampus with MEG

Ljubica Zotovic, Krista L. Lanctôt, Melisa Gumus, Michael L. Mack et al.
Alzheimer s & Dementia
Neurobiology of Language and Bilingualism
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Age influence on repetition suppression revealed in the hippocampus with MEG

Ljubica Zotovic, Krista L. Lanctôt, Melisa Gumus, Michael L. Mack, Richard Wennberg, Luís Garcia Dominguez, Mary Pat McAndrews, Wen Jia Zhao, Sandra E. Black
article en

Abstract

Neural tuning of the hippocampus during memory formation, namely repetition suppression, changes with age; expressed as greater neural activation in healthy older adults. Characterizing the aging effects on repetition suppression may offer a promising avenue for examination of hippocampal hyperexcitability as a potential biomarker for AD.

Alzheimer s & DementiaVol. 21(S2)
University Health Network (CA), University of Toronto (CA), Toronto Western Hospital (CA), Sunnybrook Hospital (CA), Sunnybrook Research Institute
Openalex Percentile: Top 32%
Neurobiology of Language and Bilingualism
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