Betweenness centrality as neurophysiological marker of DMN functional connectivity in asymptomatic carriers of PSEN1 E280A for ADAD
Bc idifferentiates between aC and nC. It is higher in nC, indicating that, at a local level, there is a greater number of nodes through which more connections pass, making them central to DMN connectivity. The local changes in aC are attributed to pathophysiological alterations in information distribution and the reorganization of DMN to distribute information across RSN and preserve cognitive functions.
Authors
- M. E. Ramirez
- Claudia Aponte (ORCID: https://orcid.org/0000-0002-3982-2509)
- Carlos Tobón (ORCID: https://orcid.org/0000-0002-5787-6279)
- John Fredy Ochoa Gómez (ORCID: https://orcid.org/0000-0002-0996-3263)
- David Fernando Aguillón Niño (ORCID: https://orcid.org/0000-0003-2283-536X)
- Lisset Zea
- Laura García
Institutions
- Universidad de Antioquia (CO)
- Instituto Neurológico de Colombia (CO)
- Antioquia Institute of Technology (CO)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_104007
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00