Epidemiological and clinical profile of malaria patients in Isfahan Province, Iran: a retrospective analysis from 2009 to 2025

Malaria incidence in Isfahan Province has markedly declined over the past 16 years; however, imported cases, predominantly among migrant workers, remain the central challenge to elimination. The dominance of P. vivax alongside the clinical severity of P. falciparum highlights the need for species-specific strategies. Strengthened cross-border collaboration, targeted interventions for migrant populations, and enhanced surveillance in high-risk rural areas are essential to sustain elimination efforts.