Decoding anoikis-related genes in lung adenocarcinoma brainmetastasis via single-cell RNA sequencing: CD44-mediated functions
Our findings indicate that epithelial cells undergo profound changes during lung cancer brain metastasis. ARGs, particularly CD44, play a critical role in this process and have prognostic significance for lung cancer brain metastasis.
Authors
- Haifeng Xia (ORCID: https://orcid.org/0000-0002-1005-1894)
- Tao Zheng (ORCID: https://orcid.org/0000-0002-1820-1762)
- Ke Xie
- Shuang Li
- Zhengzheng Ni
Institutions
- Wannan Medical College (CN)
- Soochow University (CN)
- Ruihua Affiliated Hospital of Soochow University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
- First Affiliated Hospital of Wannan Medical College (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1186/s12885-025-15485-y
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00