Neurological manifestations and MMP8 as a prognostic biomarker in severe fever with thrombocytopenia syndrome

Neurological symptoms during the early stages of SFTS are strongly associated with patient outcomes. MMP8 may serve as a potential biomarker for SFTS prognosis. The integration of clinical neurological symptoms and MMP8 measurement offers a novel framework for improving prognostic accuracy and guiding personalized management strategies in SFTS patients.

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Publication Details

Journal
PLoS neglected tropical diseases
Published
2025-12-26
DOI
https://doi.org/10.1371/journal.pntd.0013875
Primary Topic
Viral Infections and Vectors
Type
article
Field-Weighted Citation Impact
0.00
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article

Neurological manifestations and MMP8 as a prognostic biomarker in severe fever with thrombocytopenia syndrome

Lingtong Huang, Bei Jia, Qing Zhao, Haolin Song et al.
PLoS neglected tropical diseases
Viral Infections and Vectors
article

Neurological manifestations and MMP8 as a prognostic biomarker in severe fever with thrombocytopenia syndrome

Lingtong Huang, Bei Jia, Qing Zhao, Haolin Song, Qiuhong Liu, Wei Wu, Jie Wang, Ziling Cheng, Qi Xia, Jie Li, Yi Zhang
article en

Abstract

Neurological symptoms during the early stages of SFTS are strongly associated with patient outcomes. MMP8 may serve as a potential biomarker for SFTS prognosis. The integration of clinical neurological symptoms and MMP8 measurement offers a novel framework for improving prognostic accuracy and guiding personalized management strategies in SFTS patients.

PLoS neglected tropical diseasesVol. 19(12)
Nanjing Drum Tower Hospital (CN), First Affiliated Hospital Zhejiang University (CN)
Good health and well-being
Openalex Percentile: Top 31%
Viral Infections and Vectors
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