Multimodality Imaging in Cardiac Amyloidosis

Cardiac amyloidosis is an underdiagnosed cause of heart failure characterized by extracellular deposition of misfolded proteins. Advances in non-invasive imaging, including echocardiography, cardiac magnetic resonance imaging (CMR), and radionuclide imaging, have significantly enhanced the diagnostic accuracy and monitoring of cardiac amyloidosis. This review explores the role of each modality, their individual strengths, and current consensus recommendations. Emphasis is placed on the integration of multimodal imaging to guide diagnosis, prognosis, and therapeutic decisions in both AL and ATTR amyloidosis.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2025-12-25
DOI
https://doi.org/10.3390/jcm15010163
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
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article

Multimodality Imaging in Cardiac Amyloidosis

Mahi L. Ashwath, Mayuresh Chaudhari
Journal of Clinical Medicine
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Multimodality Imaging in Cardiac Amyloidosis

Mahi L. Ashwath, Mayuresh Chaudhari
article en

Abstract

Cardiac amyloidosis is an underdiagnosed cause of heart failure characterized by extracellular deposition of misfolded proteins. Advances in non-invasive imaging, including echocardiography, cardiac magnetic resonance imaging (CMR), and radionuclide imaging, have significantly enhanced the diagnostic accuracy and monitoring of cardiac amyloidosis. This review explores the role of each modality, their individual strengths, and current consensus recommendations. Emphasis is placed on the integration of multimodal imaging to guide diagnosis, prognosis, and therapeutic decisions in both AL and ATTR amyloidosis.

Journal of Clinical MedicineVol. 15(1)
The University of Texas at San Antonio Health Science Center (US), San Antonio Endovascular & Heart Institute (US)
Good health and well-being
Openalex Percentile: Top 36%
Amyloidosis: Diagnosis, Treatment, Outcomes
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