Genistein as a Therapeutic Agent in the Prodromal Phase of Alzheimer's Disease: Systematic Review

Genistein has been shown to improve cognitive function and reduce beta-amyloid deposition in patients with prodromal Alzheimer's disease. However, small sample sizes and variability in dosages limit the generalizability of these findings. Future trials with larger cohorts and standardized protocols are needed to validate these results.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70859_103969
Primary Topic
Phytoestrogen effects and research
Type
article
Field-Weighted Citation Impact
0.00
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article

Genistein as a Therapeutic Agent in the Prodromal Phase of Alzheimer's Disease: Systematic Review

Kevin Gustavo dos Santos Silva, Carlos Rocha Oliveira, Grazielle Larissa Fonte Alves, Vinícius Ferreira Souza
Alzheimer s & Dementia
Phytoestrogen effects and research
article

Genistein as a Therapeutic Agent in the Prodromal Phase of Alzheimer's Disease: Systematic Review

Kevin Gustavo dos Santos Silva, Carlos Rocha Oliveira, Grazielle Larissa Fonte Alves, Vinícius Ferreira Souza
article en

Abstract

Genistein has been shown to improve cognitive function and reduce beta-amyloid deposition in patients with prodromal Alzheimer's disease. However, small sample sizes and variability in dosages limit the generalizability of these findings. Future trials with larger cohorts and standardized protocols are needed to validate these results.

Alzheimer s & DementiaVol. 21(S5)
Anhembi Morumbi University (BR), Universidade Federal de São Paulo (BR)
Quality Education
Openalex Percentile: Top 29%
Phytoestrogen effects and research
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