Integrated Multi‐Omics Analysis Reveals Molecular Mechanisms and Identifies Potential Therapeutic Targets for Dementia

This study provides a comprehensive multi-omics framework for understanding the molecular mechanisms of dementia, identifying predictive biomarkers, and uncovering potential therapeutic targets. Our findings highlight the dynamic evolution of multi-omics profiles before dementia onset and offer new avenues for early intervention and drug repurposing.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_103240
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Integrated Multi‐Omics Analysis Reveals Molecular Mechanisms and Identifies Potential Therapeutic Targets for Dementia

Xiao‐Yu He, Jin‐Tai Yu
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Integrated Multi‐Omics Analysis Reveals Molecular Mechanisms and Identifies Potential Therapeutic Targets for Dementia

Xiao‐Yu He, Jin‐Tai Yu
article en

Abstract

This study provides a comprehensive multi-omics framework for understanding the molecular mechanisms of dementia, identifying predictive biomarkers, and uncovering potential therapeutic targets. Our findings highlight the dynamic evolution of multi-omics profiles before dementia onset and offer new avenues for early intervention and drug repurposing.

Alzheimer s & DementiaVol. 21(S2)
Fudan University (CN), Huashan Hospital (CN)
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
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Integrated Multi‐Omics Analysis Reveals Molecular Mechanisms and Identifies Potential Therapeutic Targets for Dementia — Xiao‐Yu He, Jin‐Tai Yu · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS