Long‐term effects of gamma frequency sensory stimulation after 30 months in patients with mild Alzheimer’s disease: Evidence supporting potential disease modification
Gamma frequency light and sound stimulation can be safely used daily for 30 months and slows AD-related degeneration. Induced neural activity using sensory stimulation at 40Hz shows promise as a novel disease modifying therapeutic for Alzheimer's dementia.
Authors
- Alexandra Touroutoglou (ORCID: https://orcid.org/0000-0001-9679-2433)
- Michael Brickhouse
- Emery N. Brown (ORCID: https://orcid.org/0000-0003-2668-7819)
- Elizabeth B. Klerman (ORCID: https://orcid.org/0000-0002-7402-3171)
- Brennan Jackson
- Erin Kitchener
- Noah Milman (ORCID: https://orcid.org/0000-0003-0688-0427)
- R. Philips
- Gabrielle de Weck
- Edward S. Boyden
- Monica Zheng
- M. J. Quay
- Li‐Huei Tsai
- Brad C. Dickerson
- Erika Ruiz
- Andrew Becker
- Kenji Aoki
- Ute Geigenmuller
- Diane Chan
- Vanesa Fernandez Avalos
Institutions
- Broad Institute (US)
- University of Hawaiʻi at Mānoa (US)
- Howard Hughes Medical Institute (US)
- Harvard University (US)
- William James College (US)
- Oregon Health & Science University (US)
- Harvard University Press (US)
- University of California San Diego (US)
- Massachusetts General Hospital (US)
- Massachusetts Institute of Technology (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_107168
- Primary Topic
- Photoreceptor and optogenetics research
- Type
- article
- Field-Weighted Citation Impact
- 0.00