Plasma Bile Acid Profiling Reveals Novel Early Diagnostic Biomarkers for Pediatric Sepsis

Our results highlight the potential of bile acid profiling as a diagnostic and prognostic biomarker for pediatric sepsis. These findings suggest a path toward early intervention, improving patient outcomes by enabling timely detection and treatment.

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Publication Details

Journal
Journal of Inflammation Research
Published
2025-12-01
DOI
https://doi.org/10.2147/jir.s541871
Primary Topic
Renal function and acid-base balance
Type
article
Field-Weighted Citation Impact
0.00

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article

Plasma Bile Acid Profiling Reveals Novel Early Diagnostic Biomarkers for Pediatric Sepsis

K X Li, Yuanmei Chen, Jianfeng Liu, Li Fan et al.
Journal of Inflammation Research
Renal function and acid-base balance
article

Plasma Bile Acid Profiling Reveals Novel Early Diagnostic Biomarkers for Pediatric Sepsis

K X Li, Yuanmei Chen, Jianfeng Liu, Li Fan, L Guo, Danni He, Xiuxiu Lu, Lipeng Zhang, Zhongyuan Sun, Wei Li, Ning Li, Qi Zhang, Yuanyuan Wang
article en

Abstract

Our results highlight the potential of bile acid profiling as a diagnostic and prognostic biomarker for pediatric sepsis. These findings suggest a path toward early intervention, improving patient outcomes by enabling timely detection and treatment.

Journal of Inflammation ResearchVol. Volume 18
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Beijing Chao-Yang Hospital, Capital Medical University (CN), China-Japan Friendship Hospital (CN), Beijing Tian Tan Hospital (CN), National Clinical Research Center for Digestive Diseases (CN), Capital Institute of Pediatrics (CN), Guangzhou Women and Children Medical Center (CN), Beijing Children’s Hospital (CN), Affiliated Zhongshan Hospital of Dalian University (CN), Qilu Hospital of Shandong University (CN), Guangzhou Medical University (CN)
China-Japan Friendship Hospital
Good health and well-being
Openalex Percentile: Top 31%
Renal function and acid-base balance
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