Selenium‐Based Molecules to Treat Alzheimer’s Disease
This study led to the identification of novel selenium-based small molecules (N-benzylphenoselenazines) that are able to reduce Aβ40 aggregation and demonstrate antioxidant activity suggesting their potential application as disease-modifying agents to treat AD.
Authors
- Arash Shakeri
- Rahul C Karuturi
- Ahmed Abdallah Hefny
- Praveen Nekkar Rao
Institutions
- University of Waterloo (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_103404
- Primary Topic
- Organoselenium and organotellurium chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00