Aggressive biological behavior of benign central nervous system neoplasms: The case of hemorrhagic subependymomas – An illustrated review

Bleeding increases both the severity of initial clinical symptoms and the complexity of the radiological differential diagnosis of SEs but does not seem to influence strongly the degree of surgical resection of these otherwise histologically benign neoplasms. Both the exact topography of the hSE within the ventricular system and the presence of intraparenchymal extension of the neoplasm and/or the associated bleeding could negatively affect the final clinical outcome.