Experimental evolution of Plasmodium yoelii in single and helminth-coinfected mice

We did not find strong evidence supporting a divergence between the virulence of SI-lines and COI-lines, possibly due to the cost of virulence paid by COI-lines. However, Py rapidly adapted to the environmental conditions provided by single infected or coinfected hosts, as shown by the slower replication rate found in mismatched-environment trials.

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Publication Details

Journal
Malaria Journal
Published
2025-12-26
DOI
https://doi.org/10.1186/s12936-025-05764-1
Primary Topic
Malaria Research and Control
Type
article
Field-Weighted Citation Impact
0.00
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article

Experimental evolution of Plasmodium yoelii in single and helminth-coinfected mice

Emma Groetz, Gabriele Sorci, Mickaël Rialland, Bruno Faivre et al.
Malaria Journal
Malaria Research and Control
article

Experimental evolution of Plasmodium yoelii in single and helminth-coinfected mice

Emma Groetz, Gabriele Sorci, Mickaël Rialland, Bruno Faivre, Aloïs Dusuel, Benjamin Roche, Luc Bourbon
article en

Abstract

We did not find strong evidence supporting a divergence between the virulence of SI-lines and COI-lines, possibly due to the cost of virulence paid by COI-lines. However, Py rapidly adapted to the environmental conditions provided by single infected or coinfected hosts, as shown by the slower replication rate found in mismatched-environment trials.

Malaria JournalVol. 25(1)
Centre National de la Recherche Scientifique (FR), Inserm (FR), Université de Bourgogne (FR), Université de Montpellier (FR), Maladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle (FR), Centre de recherche Translationnelle en Médecine moléculaire (FR), Biogéosciences (FR), Institut de Recherche pour le Développement (FR)
Openalex Percentile: Top 26%
Malaria Research and Control
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