Retinal layer thickness as biomarker for cognitive decline in rhesus macaques

Rhesus macaques showed aging behaviors and retinal layer measurements similar to humans. Although behavioral testing poses challenges, retinal imaging was highly reproducible. A larger, longitudinal study pairing behavioral assessments with retinal measurements is needed to determine if the retina could serve as a noninvasive biomarker of cognitive function in preclinical NHP research.

Authors

Yin Liu (ORCID: https://orcid.org/0000-0003-4483-9951)

Institutions

University of California, Davis (US)

Publication Details

Journal: Alzheimer s & Dementia
Published: 2025-12-01
DOI: https://doi.org/10.1002/alz70856_103383
Primary Topic: Glaucoma and retinal disorders
Type: article
Field-Weighted Citation Impact: 0.00

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article

Retinal layer thickness as biomarker for cognitive decline in rhesus macaques

Yin Liu

Dec 1, 2025

Alzheimer s & Dementia

Glaucoma and retinal disorders

article

Retinal layer thickness as biomarker for cognitive decline in rhesus macaques

Yin Liu

December 1, 2025article en

Abstract

Alzheimer s & DementiaVol. 21(S2)

University of California, Davis (US)

Openalex Percentile: Top 29%

Glaucoma and retinal disorders

DOI Open Access PDF OpenAlex

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Retinal layer thickness as biomarker for cognitive decline in rhesus macaques — Yin Liu · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS