<i>Tinospora cordifolia</i> attenuates cognitive impairment in rats with vascular dementia by suppressing TLR4/MyD88/NF‐κB signaling pathway induced neuroinflammation.
The findings suggest that T. cordifolia may alleviate cognitive dysfunction in VaD by modulating the TLR4/MyD88/NF-κB inflammatory signaling pathway. This herb shows promise as a potential therapeutic agent and TLR4 inhibitor for the treatment of VaD.
Authors
- Abhishek Pathak (ORCID: https://orcid.org/0000-0003-4890-4511)
- Devesh Kumar
- Gajendra T A
- Sairam Krishnamurthy
Institutions
- Institute of Medical Sciences (IN)
- Indian Institute of Technology BHU (IN)
- Banaras Hindu University (IN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70858_102042
- Primary Topic
- Medicinal Plants and Neuroprotection
- Type
- article
- Field-Weighted Citation Impact
- 0.00