Association Between Respiratory Viral Infection and Peripheral T Lymphocyte Subsets in Elderly Patients With Acute Exacerbation of Bronchiectasis

Viral infections are frequent in elderly bronchiectasis patients with AEB and are characterized by reduced CD4<sup>+</sup> T-cell counts, lower CD4<sup>+</sup>/CD8<sup>+</sup> ratios, and heightened inflammatory responses, reflecting underlying age-related immune vulnerability.

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Publication Details

Journal
The Clinical Respiratory Journal
Published
2025-12-01
DOI
https://doi.org/10.1111/crj.70151
Primary Topic
Respiratory viral infections research
Type
article
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article

Association Between Respiratory Viral Infection and Peripheral T Lymphocyte Subsets in Elderly Patients With Acute Exacerbation of Bronchiectasis

Yuan Zhi, Jun Qin, Jing Zheng, Yuan Zhuang et al.
The Clinical Respiratory Journal
Respiratory viral infections research
article

Association Between Respiratory Viral Infection and Peripheral T Lymphocyte Subsets in Elderly Patients With Acute Exacerbation of Bronchiectasis

Yuan Zhi, Jun Qin, Jing Zheng, Yuan Zhuang, Guoping Zhang, Qun Wang, Sai Wang
article en

Abstract

Viral infections are frequent in elderly bronchiectasis patients with AEB and are characterized by reduced CD4<sup>+</sup> T-cell counts, lower CD4<sup>+</sup>/CD8<sup>+</sup> ratios, and heightened inflammatory responses, reflecting underlying age-related immune vulnerability.

The Clinical Respiratory JournalVol. 19(12)
Ningbo No. 2 Hospital (CN), Ningbo No.6 Hospital (CN)
Openalex Percentile: Top 30%
Respiratory viral infections research
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