Correlation of prefrontal-based resting state functional connectivity with the degree of cognitive impairment in Alzheimer’s disease: a functional near-infrared spectroscopy study
FC strength in the left dorsolateral PFC, where BA46.L and BA9.L are located, emerged as a key region for cortical dysfunction in cognitive impairment. Moreover, there were differences in FC across levels of cognitive impairment, and significant correlations between differences in FC strength in BA brain regions and cognitive level.
Authors
- Jiaqi Song (ORCID: https://orcid.org/0009-0004-6630-5226)
- Wenbo Zhang (ORCID: https://orcid.org/0009-0005-8492-6744)
- Fuxin Zhong (ORCID: https://orcid.org/0000-0001-8370-6639)
- Ming Chen (ORCID: https://orcid.org/0000-0001-9869-4036)
- Qi Tian (ORCID: https://orcid.org/0000-0002-3149-6024)
- Weihua Yu
- Yingxi Chen
- Yang Lü
- Yiming Guo
- Mengyu Yan
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Behavioral and Brain Functions
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1186/s12993-025-00316-8
- Primary Topic
- Optical Imaging and Spectroscopy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00