Source localization of neural substrates required for generating a gamma frequency response to 40Hz GENUS light and sound stimulation

For the first time, we provide evidence of target engagement and sources of gamma wave generation in the brain that are important for sensory processing, associative and executive memory functions and areas affected by AD pathology when humans are undergoing 40Hz GENUS light and sound stimulation. This data set can serve as a resource for exploring responses of neural substrates of 40Hz visual and auditory stimulation.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70859_107067
Primary Topic
Electromagnetic Fields and Biological Effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Source localization of neural substrates required for generating a gamma frequency response to 40Hz GENUS light and sound stimulation

Guillaume Leclerc, Dimitrios Pantazis, Brennan Jackson, Andrew Becker et al.
Alzheimer s & Dementia
Electromagnetic Fields and Biological Effects
article

Source localization of neural substrates required for generating a gamma frequency response to 40Hz GENUS light and sound stimulation

Guillaume Leclerc, Dimitrios Pantazis, Brennan Jackson, Andrew Becker, R. Philips, Edward S. Boyden, Monica Zheng, M. J. Quay, Li‐Huei Tsai, Natalie Hahn, Erika Ruiz, Samantha Yee, Xinran Zhang, Emery N Brown, Ute Geigenmuller, Diane Chan
article en

Abstract

For the first time, we provide evidence of target engagement and sources of gamma wave generation in the brain that are important for sensory processing, associative and executive memory functions and areas affected by AD pathology when humans are undergoing 40Hz GENUS light and sound stimulation. This data set can serve as a resource for exploring responses of neural substrates of 40Hz visual and auditory stimulation.

Alzheimer s & DementiaVol. 21(S5)
Broad Institute (US), Howard Hughes Medical Institute (US), Princeton University (US), University of Massachusetts Amherst (US), University of Oxford (GB), Massachusetts General Hospital (US), Massachusetts Institute of Technology (US)
Openalex Percentile: Top 21%
Electromagnetic Fields and Biological Effects
DOIOpen Access PDFOpenAlex
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Source localization of neural substrates required for generating a gamma frequency response to 40Hz GENUS light and sound stimulation — Guillaume Leclerc, Dimitrios Pantazis, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS