Alzheimer Disease Drugs in bvFTD: Real‐World Clinical Utilization and Behavioral Impact

Our analysis showed that nearly 50% of bvFTD patients were treated with AchE inhibitors and/or memantine. Despite the lack of robust evidence supporting their efficacy in FTD, our results suggest that these medications may have a positive impact on behavior, comportment, and personality. However, participants using these drugs also required more antidepressants. These findings indicate that well-designed studies are essential to determine effectiveness and safety of AchE inhibitors and memantine in this population.