Cognitively‐defined AD dementia subgroups have different MRI white matter hyperintensity distribution in a community‐based cohort

Increased occipital WMH in AD-Visuospatial may suggest white matter damage is part of the mechanism of visuospatial impairment. AD-Executive estimates demonstrated increased WMH in most areas though only achieved significance in some listed above. The relatively low WMH in the temporal lobe demonstrated in both AD-Memory and AD-Language may suggest white matter damage is a less important part of the mechanism of impairment.