The angiosome and woundosome concepts in guiding revascularization for chronic limb-threatening ischemia and diabetic foot ulcers—a narrative review

Incorporating angiosome- and woundosome-based strategies in CLTI management may improve limb- and patient-related outcomes. The decision on which particular territory needs primary attention and how many vessels require revascularization largely depends on the patency of feeding arteries in the wound area. In the future, a standardized way to measure the intra- and post-procedural arterial flow to the wound would be necessary, to study the clinical applications of the mentioned strategies. Future studies should therefore prospectively validate woundosome-guided strategies and integrate standardized perfusion assessment tools to guide individualized treatment decisions.