Targeted Next‐Generation Sequencing of the Leptin‐Melanocortin Pathway in Severe Obesity
This supports the relevance of expanded genetic testing in severe obesity. Early-onset obesity remains a key clinical feature to guide genetic investigation and identify patients who may benefit from early personalized care and targeted treatments.
Authors
- C. Poitou
- Nathan Faccioli
- F Bertin
- Pauline Faucher
- Blandine Gatta‐Cherifi (ORCID: https://orcid.org/0000-0002-7399-1330)
- Mathieu Georget (ORCID: https://orcid.org/0000-0002-7963-8124)
- Claire Carette
- Karine Clément
- Julie Gonneau‐Lejeune
- Béatrice Dubern
- Ahlam Azar‐Kolakez
- Johanne Le Beyec‐Le Bihan
- Agnès Linglart
Institutions
- Université de Bordeaux (FR)
- Inserm (FR)
- Sorbonne Université (FR)
- Centre Hospitalier Universitaire de La Réunion (RE)
- Nutrition et obésité : approches systémiques (FR)
- Hôpital Européen Georges-Pompidou (FR)
- Hôpital Cardiologique du Haut-Lévêque (FR)
- Pitié-Salpêtrière Hospital (FR)
- Hôpital Robert-Debré (FR)
- Centre de Recherche sur l'Inflammation (FR)
- Hôpital Louis Pradel (FR)
- Bicêtre Hospital (FR)
Publication Details
- Journal
- Obesity
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1002/oby.70107
- Primary Topic
- Regulation of Appetite and Obesity
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Novo Nordisk