Estimating the Prevalence of Alzheimer's Disease Pathology Using Plasma Biomarkers in COMPASS‐ND

The plasma biomarkers assays tested have high specificity for detecting AD pathology, enabling their use to estimate AD pathology in a larger cohort. Based on the low sensitivity of the plasma biomarkers tested, we assume that these results underestimate the prevalence of AD pathology in the COMPASS-ND cohort.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_103330
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Estimating the Prevalence of Alzheimer's Disease Pathology Using Plasma Biomarkers in COMPASS‐ND

David H. Yang, Johnny W. Huang, Sophie Stukas, Cheryl L. Wellington et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Estimating the Prevalence of Alzheimer's Disease Pathology Using Plasma Biomarkers in COMPASS‐ND

David H. Yang, Johnny W. Huang, Sophie Stukas, Cheryl L. Wellington, Mari L. DeMarco, Bruna Seixas Lima, Durjoy Lahiri, Nyra Ahmed, Howard Chertkow, Jennifer G Cooper
article en

Abstract

The plasma biomarkers assays tested have high specificity for detecting AD pathology, enabling their use to estimate AD pathology in a larger cohort. Based on the low sensitivity of the plasma biomarkers tested, we assume that these results underestimate the prevalence of AD pathology in the COMPASS-ND cohort.

Alzheimer s & DementiaVol. 21(S2)
University of British Columbia (CA), University of Toronto (CA), Queen's University (CA), Baycrest Hospital (CA)
Openalex Percentile: Top 32%
Dementia and Cognitive Impairment Research
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