Chemotherapy-induced cognitive impairment (CICI): A systematic-narrative review of systematic reviews

This review identifies the most frequently affected neurocognitive domains and subdomains, and specifies the batteries, screenings and tests most commonly employed in their assessment. This study proposes a three-stage model for improved evaluation: (1) application of a comprehensive neurocognitive screening, (2) administration of prioritized domain-specific tests, and (3) inclusion of subjective measures addressing cognitive complaints and quality of life. This integrative framework aims to enhance the accuracy and clinical utility of CICI assessment.

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Publication Details

Journal
Applied Neuropsychology Adult
Published
2025-12-26
DOI
https://doi.org/10.1080/23279095.2025.2608106
Primary Topic
Cancer-related cognitive impairment studies
Type
article
Field-Weighted Citation Impact
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article

Chemotherapy-induced cognitive impairment (CICI): A systematic-narrative review of systematic reviews

F. del Río, Rodrigo Vega, Gabriel Max Sepulveda
Applied Neuropsychology Adult
Cancer-related cognitive impairment studies
article

Chemotherapy-induced cognitive impairment (CICI): A systematic-narrative review of systematic reviews

F. del Río, Rodrigo Vega, Gabriel Max Sepulveda
article en

Abstract

This review identifies the most frequently affected neurocognitive domains and subdomains, and specifies the batteries, screenings and tests most commonly employed in their assessment. This study proposes a three-stage model for improved evaluation: (1) application of a comprehensive neurocognitive screening, (2) administration of prioritized domain-specific tests, and (3) inclusion of subjective measures addressing cognitive complaints and quality of life. This integrative framework aims to enhance the accuracy and clinical utility of CICI assessment.

Applied Neuropsychology Adult
Clínica Alemana (CL), Universidad de las Américas (NI), Universidad de Las Américas (EC)
Reduced inequalities
Openalex Percentile: Top 28%
Cancer-related cognitive impairment studies
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