Nutrition’s Impact on Recovery in Craniofacial and Otorhinolaryngological Injuries: Considering Areas of Armed Conflict and Humanitarian Emergencies

Head-and-neck trauma can often create a double burden wherein metabolic demand surges just as oral intake is curtailed by pain, dysphagia, fixation, airway protection, and procedure-related restrictions. This article argues that nutrition often becomes the rate-limiting step of recovery in craniofacial and otorhinolaryngological injuries. We synthesize how the neuroendocrine stress–metabolic response drives hypercatabolism and immune activation, and how malnutrition can derail these adaptive programs by impairing collagen deposition, angiogenesis, leukocyte function, and the oral microbiome, and thereby raising the risk of infection and potentially delaying wound closure, speech, mastication, swallowing, and psychosocial reintegration. We then map some of the compounding effects of armed conflict and humanitarian crises, wherein the absence of robust medical and humanitarian aid and coupled with resource shortages, patients may be pushed into states of poorer health outcomes.

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Publication Details

Journal
Journal of Craniofacial Surgery
Published
2025-12-26
DOI
https://doi.org/10.1097/scs.0000000000012226
Primary Topic
Child Nutrition and Water Access
Type
article
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article

Nutrition’s Impact on Recovery in Craniofacial and Otorhinolaryngological Injuries: Considering Areas of Armed Conflict and Humanitarian Emergencies

Bilal Irfan, Mohamed Kamel, Khaled Shihabi, Barock Tesfaye et al.
Journal of Craniofacial Surgery
Child Nutrition and Water Access
article

Nutrition’s Impact on Recovery in Craniofacial and Otorhinolaryngological Injuries: Considering Areas of Armed Conflict and Humanitarian Emergencies

Bilal Irfan, Mohamed Kamel, Khaled Shihabi, Barock Tesfaye, Nuha Riyad, Amir Mahdi Ghafarian, Iman Khan, Osama Ewidat, Aman Salahie
article en

Abstract

Head-and-neck trauma can often create a double burden wherein metabolic demand surges just as oral intake is curtailed by pain, dysphagia, fixation, airway protection, and procedure-related restrictions. This article argues that nutrition often becomes the rate-limiting step of recovery in craniofacial and otorhinolaryngological injuries. We synthesize how the neuroendocrine stress–metabolic response drives hypercatabolism and immune activation, and how malnutrition can derail these adaptive programs by impairing collagen deposition, angiogenesis, leukocyte function, and the oral microbiome, and thereby raising the risk of infection and potentially delaying wound closure, speech, mastication, swallowing, and psychosocial reintegration. We then map some of the compounding effects of armed conflict and humanitarian crises, wherein the absence of robust medical and humanitarian aid and coupled with resource shortages, patients may be pushed into states of poorer health outcomes.

Journal of Craniofacial SurgeryVol. 37(1/2)
Brigham and Women's Hospital (US), Midwestern University (US), Harvard University (US), An-Najah National University (PS), Vanderbilt University (US), Al-Quds University (PS), University of Medicine and Health Sciences (KN), University of Michigan (US), Center for Practical Bioethics (US), University of Oklahoma Health Sciences Center (US)
Zero hunger
Openalex Percentile: Top 35%
Child Nutrition and Water Access
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Nutrition’s Impact on Recovery in Craniofacial and Otorhinolaryngological Injuries: Considering Areas of Armed Conflict and Humanitarian Emergencies — Bilal Irfan, Mohamed Kamel, et al. · Journal of Craniofacial Surgery (2025) | TGRS Research Map | TGRS