Does Neighborhood Disadvantage Moderate the Relationship between Apolipoprotein E Status and Cognitive Functioning?

In our subsample of participants, ADI did not moderate the relationship between APOE status and performance on attention or memory measures. However, research demonstrates a relationship between environmental factors and cognitive decline. Some factors remain modifiable, on an individual and policy level, and in order to shift towards a preventative rather than reactive care model, it is imperative to continue to explore modifiable risk factors (e.g., social determinants of health) that impact cognition.