Baseline Association Between Remotely‐measured Cognitive Function and Blood Pressure in a Large, Multicenter Pragmatic Hybrid Effectiveness‐Implementation Trial

Higher systolic BP is associated with poorer performance in semantic fluency and verbal learning, independent of age and sex, yet it is not associated with global cognitive function. These findings suggest that hypertension may selectively impact specific cognitive domains, particularly those related to language and memory. Furthermore, these abilities are often affected early in AD. Future analyses will explore whether lowering BP can slow cognitive decline in the broad patient population seen in the primary care setting.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70858_104060
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Baseline Association Between Remotely‐measured Cognitive Function and Blood Pressure in a Large, Multicenter Pragmatic Hybrid Effectiveness‐Implementation Trial

Adam C. Parks, Molly A. Conroy, Diego R. Mazzotti, Kate Young et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Baseline Association Between Remotely‐measured Cognitive Function and Blood Pressure in a Large, Multicenter Pragmatic Hybrid Effectiveness‐Implementation Trial

Adam C. Parks, Molly A. Conroy, Diego R. Mazzotti, Kate Young, Jeffrey Murray Burns, Sravani Chandaka, Mark A. Supiano, Xing Song, Jonathan D Mahnken, Aditi Gupta
article en

Abstract

Higher systolic BP is associated with poorer performance in semantic fluency and verbal learning, independent of age and sex, yet it is not associated with global cognitive function. These findings suggest that hypertension may selectively impact specific cognitive domains, particularly those related to language and memory. Furthermore, these abilities are often affected early in AD. Future analyses will explore whether lowering BP can slow cognitive decline in the broad patient population seen in the primary care setting.

Alzheimer s & DementiaVol. 21(S4)
University of Utah (US), University of Kansas Medical Center (US), University of Missouri (US)
Openalex Percentile: Top 32%
Dementia and Cognitive Impairment Research
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